Muhammad Mumtaz
King Salman Hospital, KSA
Title: Can there be a correlation established between characteristic histological and radiographical findings in adenomatoid odontogenic tumor? A case report
Biography
Biography: Muhammad Mumtaz
Abstract
Adenomatoid odontogenic tumor (AOT) is an uncommon, benign epithelial lesion of odontogenic origin which mostly
affects the young individuals. As per literature the mean age of presentation is 13.2 years, female to male ratio is 2.3:1 and
is most commonly found in maxilla (maxilla to mandible ratio is 2.6:1). It is usually associated with an impacted tooth which
may be grossly displaced. Recommended treatment can vary from enucleation to resection of the tumor. In our case, we have
attempted to establish the characteristic correlation between histological and radiological parameters. In this case report a 13
year old female was presented with painless swelling (4×4 cm) on left side of her face. Intraoral examination shows unerupted
canine, premolars and molars of the ipsilateral side. Histopathological report suggested it to be an adenomatoid odontogenic
tumor. Immunohistochemical stains including Ki-67, p53, BCL2 was done to see the proliferation and aggressiveness of the
tumor. Orthopantomogram was done initially to see the status of unerupted teeth; CT scan was advised to see the extent of
lesion and displacement of teeth. The aggressiveness of bone destruction on radiograph and CT scan were misleading initially
towards dentigerous cyst but the characteristic infiltrating bony destruction was suggestive of more aggressive pathology.
Histological parameters obtained using immunohistochemistry facilitated the diagnosis of